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1994-10-25
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Document 2419
DOCN M94A2419
TI Ante & post natal HIV screening in Bombay-India.
DT 9412
AU Merchant RH; Gilada IS; Mahajan RP; Agarwal JG; Mehta AC; Wadia
Maternity Hospital, Parel, Bombay.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):309 (abstract no. PC0165). Unique
Identifier : AIDSLINE ICA10/94370156
AB OBJECTIVE: To determine incidence of HIV antibodies in the antenatal
population in a large urban city in India and clinically & serologically
evaluate infants born to those women who tested HIV positive. METHODS:
Over a 13 month period ending 1994 January, 13,977 pregnant women were
screened for the presence of HIV antibodies at the Wadia Maternity
Hospital, Bombay, India. Blood was tested by Rapid Elavia mixt screening
test for HIV1 and HIV2 antibodies (Sanofi Diagnostics Pasteur-France &
Genetic Systems Corp USA) by ELISA technique. Infants born to HIV
positive mothers are being clinically assessed at the 3 monthly
intervals and will be tested at 6, 12 & 18 months for the presence of
HIV antibodies. RESULTS: 97 women (.69%) tested positive at the first
visit, while only 58 came for follow up serotesting, of which 43 have
delivered to date. All cord blood samples tested (n = 40) were positive
for HIV antibodies. 52 sexual partners of these 58 women were available
for testing and 51 tested seropositive. 4 of these 58 women tested
serologically positive for syphilis, while only one was a commercial sex
worker. Of 43 who delivered, 39 were live born with mean birth weight of
2500 gm and mean gestation of 38.2 weeks. No infant had congenital
malformation. CONCLUSION: To date no infant followed up clinically upto
6 months post delivery has exhibited clinical evidences to suggest
active HIV infection. All 12 infants serotested so far at 6 months age
have tested positive for HIV antibodies. Given the large number of
deliveries in India (20-22 million per annum), and a prevalence rate of
approximately 0.7% in the urban population, this disorder poses a major
problem in the future.
DE *AIDS Serodiagnosis Female Human HIV
Infections/DIAGNOSIS/TRANSMISSION *HIV Seropositivity Infant, Newborn
*Neonatal Screening Pregnancy Pregnancy Complications,
Infectious/*DIAGNOSIS MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).